There's plenty in life to knock you down and keep you from pursuing what God is calling you to do.
This includes things like: illness, financial pressure, personal failings and guilt, relationship difficulties, concerns about others, discouragement and more.
In our fallen world, these issues WILL affect you.
Often!
But the truth you have to cling to is this:
No matter how much you get knocked down by adversity... and even just worries... God will give you the grace to get up again when you look to Him... so you can refocus on His purpose for you and walk in it.
"The righteous falls seven times and rises again..." (Pr.24:16).